After the loss of their mother due to illness, brothers Edward and Alphonse Elric attempt to resurrect her through use of the universally taboo Human Transmutation, a forbidden branch of Alchemy; in the process, Edward loses his left leg and Alphonse is taken through the Doors of Truth. in order to at least save his brother, Edward sacrifices his right arm to affix Alphonse's soul to a suit of armor. After a few days, Edward is approached by Roy Mustang, an officer with the State Military, who suuggests he become a State Alchemist to gain access to top-secret materials that could help them find a way to regain their bodies. Edward's missing arm and leg are replaced with advanced mechanical prosthetics known as automail, and along with his brother, he sets out to find a way to return them both to normal, while fighting Homunculi, the reanimated super-powered offshoots of failed Human Transmutation, and eventually the Northern Briggs Army. Eventually, at the cost of his ability to perform alchemy, Edward manages to restore Alphonse to his body, and after two years the brothers separate to repay those who helped them along their journey.